Comparison of different drug susceptibility test methods to detect the 1 rifampin heteroresistance in Mycobacterium tuberculosis
نویسندگان
چکیده
23 We compared the efficiency of different drug susceptibility testing methods to detect 24 the rifampin (RIF) heteroresistance in Mycobacterium tuberculosis. Our data revealed 25 that broth dilution method found more resistance than MGIT (P=0.046) for low 26 resistance group. Similarly, broth dilution method was more sensitive to detect RIF 27 heteroresistance in subpopulation with slow grow rate than MGIT (P=0.033). In 28 conclusion, our data demonstrated that the broth dilution method was more sensitive 29 than MGIT to detect RIF heteroresistance. 30
منابع مشابه
Comparison of different drug susceptibility test methods to detect rifampin heteroresistance in Mycobacterium tuberculosis.
We compared the efficiencies of different drug susceptibility testing methods in detecting rifampin (RIF) heteroresistance in Mycobacterium tuberculosis. Our data revealed that the broth dilution method found more resistance than MGIT did (P=0.046) for the low-resistance group. Similarly, the broth dilution method was more sensitive in detecting RIF heteroresistance in subpopulations with low g...
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